EU regulators have put clean nails in the spotlight by classifying TPO as a CMR category 1B substance, in this case a presumed reproductive toxicant. Previously allowed at up to 5% in professional nail gels, it is now prohibited entirely in EU cosmetics under the Omnibus VII update. Here is what that means for your next gel manicure.
Key Takeaways
- Since September 1, 2025, TPO-containing cosmetics cannot be sold or used in the EU.
- The ban rests mainly on animal data on fertility.
- Several brands now sell TPO-free gels; check ingredient lists.
- UV exposure and lifted gels still deserve attention everywhere.
This guide is part of our Nail Care & Clean Polish collection. For more ideas, see Nail Art & Design: The Complete Guide.
On September 1, 2025, a European Union ban on trimethylbenzoyl diphenylphosphine oxide (TPO) took effect. TPO was widely used in gel polishes and gel topcoats. This chemical, known as a photo initiator, helps topcoat nail formulas cure quickly under UV or LED light while delivering that coveted ultra-glossy finish.
Why the EU Said “No” to TPO
The classification rests mainly on animal studies showing effects on fertility. Human evidence is limited, but EU cosmetics law prohibits CMR category 1A and 1B substances unless a specific exemption is granted, and none was, so the result was a full ban.
Immediate Impact: Who Is Affected?
- Salon pros and salons across the EU must immediately stop using, selling, or distributing any TPO-containing products. There is no grace period to sell through old stock.
- Manufacturers and distributors must reformulate all products distributed in Europe or face fines and penalties.
- Consumers may notice fewer gel options in Europe unless brands have switched to TPO-free formulas.
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Brands That Already Said Goodbye to TPO
Manucurist says it left TPO out of its Green Flash™ line from the start, using TPO-L, a photoinitiator that is not classified as CMR, instead. The brand describes the formulas as vegan and up to 84 percent plant-based, with up to 12 days of wear.
Elegelli has also said all its gel products are TPO-free. Other brands and systems marketed as TPO-free include the following (formulas change, so check the ingredient list before you buy):
- OPI’s Intelli Gel system
- Aprés Nail
- Nail Creation
- Aimeili
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The U.S. Contrast: Business as Usual for Now
At the time of writing, the United States has not banned TPO. Gel nail salons in the U.S. continue using TPO-based products, although some may voluntarily switch as formulations shift globally.
Smart Moves for Mani Lovers
- Ask salons if they use TPO-free products, especially if you are cautious about potential risks.
- Space out your gel manicures, use a fortifying base coat, and ensure good ventilation during application.
- Protect your hands from the curing lamp with a broad-spectrum, water-resistant SPF 30+ sunscreen or fingerless gloves, and have lifted gels removed promptly. Moisture trapped under lifted product can lead to infections such as Pseudomonas; see a dermatologist if a nail turns green, thick, or painful.
Signing Off with a Glossy but Safe Finish
The EU’s TPO ban is a significant step for cosmetic safety, even if it rests largely on animal data. If you are in Europe, prepare for a shift in nail salon menus. And if you are elsewhere, this regulatory move might still inspire safer formulations worldwide.
Stay glossy, stay safe!
What is a top coat for nails?
A top coat is the clear final layer applied over nail polish. It seals in the color, adds shine, and helps prevent chipping and peeling. Apply it over the color coat and run it along the free edge of each nail.
When should I put a top coat on my nails?
Unless it’s humid or a slow-drying polish, it’s usually ready for the topcoat to be applied after a minute or two. Since a fast-drying top coat is made to aid in the drying of wet polish, it’s acceptable to apply it before your polish has begun to dry.
Do you really need a top coat?
Topcoat is beneficial for your nails in terms of both look and protection from normal wear and tear. It provides an additional barrier for the nail and helps maintain the polish by avoiding chipping, fading, and dullness.
Sources
- European Commission – TPO in nail products: questions and answers
- American Academy of Dermatology – Gel manicures: Tips for healthy nails
- American Academy of Dermatology – Artificial nails: Tips for reducing nail damage
- U.S. Food and Drug Administration – Nail Care Products
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Isabela Márquez del Sol is a contributing writer for Successible Life who specializes in nails, from cat eye, metallic and blooming gel designs to celebrity-inspired manicures and choosing the right top coat.